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The person waiting for calmly approached him outside a Midtown Manhattan hotel, video shows. The shooter raised a gun and fatally shot Thompson at close range. Even as the weapon appeared to jam, the shooter remained composed, standing over Thompson and firing again before walking away, leaving behind , multiple news outlets reported. The killer hasn't yet been identified by authorities and is still at large. Experts told USA TODAY these details provide investigators key clues about who the man is ‒ and how tough it will be to catch him. There's some evidence to support that, said , a professor at John Jay College of Criminal Justice at the City University of New York. The more Alcazar sees video footage of the shooting, the more he believes the shooter may have been a professional. "It looks like this guy may have had some experience, and I'm sure investigators are entertaining the possibility," added Alcazar, a former detective with the New York City Police Department. "It definitely crossed my mind." He said the shooter's choice of what appears to be a indicates he had an objective: "If this guy wanted to assassinate someone, that's a very specific weapon that just needs one shot," Alcazar said. "If that's indeed the weapon (the weapon used in the shooting has not yet been recovered) and he specifically selected that, it shows confidence." Others aren't so sure. "I would lean toward not," said , a professor of criminal justice at Michigan State University and director of the university's Intelligence program. "On the one hand, from the behavior I saw in videos of the shooting, it might indicate he was a paid professional. He seems collected, calm, he's not overtly rushing." But, added Carter, whose expertise is in violent crime control, counterterrorism and law enforcement intelligence, a professional would have made sure in advance that the weapon he planned to use was in proper working order and wouldn't jam, something which appeared to have happened. "A paid assassin would use a revolver, which is more reliable and has no cartridges, or he would pick up the cartridges," Carter said. The cartridges that were left behind, Carter observed, might also indicate a motive that leans more toward a personal grudge than a professional hit: Multiple outlets reported, citing police sources, that recovered from the scene. "There is no reason someone who's a paid killer would do that," said Carter, "because that's evidence, and it's unique evidence." The shooter appears calm because, Carter speculated, "This is about revenge: 'I am thinking revenge, and I am basking in that revenge.'" Carter said investigators have their work cut out for them, since surveillance video, cell phone activity, facial recognition technology and other digital and electronic evidence, while helpful, will also be voluminous in a place like Midtown Manhattan and going through it all will be "tremendously labor-intensive." He said that while the shooter does seem to have experience with weapons, "that could be literally hundreds of thousands of people," including military and law enforcement personnel or veterans, hunters or gun hobbyists. The shooter seems to have taken steps to plan the attack and conceal his identity, Alcazar noted, using a fake ID, wearing a face mask and staying at a hostel, not renting a car but instead fleeing the scene first on foot and then on a bike. Carter and Alcazar both believe the shooter, whether a professional assassin or a person out for revenge or with some other motive, will be caught. "He seems to have been very meticulous," both in planning and in his escape, Alcazar said. "So when they're processing the scene and gathering surveillance and evidence, (law enforcement) will have to be just as meticulous."SANTA CLARA, Calif. (AP) — Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an injury to his throwing shoulder that has already forced him to miss a game. Purdy spent the bulk of the session of Wednesday's practice open to reporters as either a spectator or executing handoffs outside of one short pass to Jordan Mason. Purdy hurt his shoulder during a loss to Seattle on Nov. 17. He tried to throw at practice last Thursday but had soreness in his right shoulder and shut it down. He missed a loss to Green Bay but was able to do some light throwing on Monday. His status for this week remains in doubt as the Niners (5-6) prepare to visit Buffalo on Sunday night. Purdy isn't the only key player for San Francisco dealing with injuries. Left tackle Trent Williams and defensive end Nick Bosa remain sidelined at practice Wednesday after missing last week's game. Williams was using a scooter to get around the locker room as he deals with a left ankle injury. Bosa has been out with injuries to his left hip and oblique. Bosa said the week off helped him make progress and that he hopes to be able to take part in individual drills later in the week. Bosa wouldn't rule out being able to play on Sunday. "It’s feeling a lot better,” Bosa said. “Still need to get better before I’m ready to go. This week will be big and I’ll know a lot more in the next couple of days.” Running back Christian McCaffrey has been able to play, but isn't back to the form that helped him win AP Offensive Player of the Year in 2023 after missing the first eight games this season with Achilles tendinitis. McCaffrey has 149 yards rushing in three games back with his 3.5 yards per carry down significantly from last season's mark of 5.4. But he is confident he will be able to get back to his usual level of play. “When you lose and maybe you don’t jump out on the stat sheet, your failures are highlighted,” he said. “I’m happy I’m out here playing football and I just know with time it will come.” Coach Kyle Shanahan said he has liked what he has seen from McCaffrey, adding that there hasn't been much room to run in recent weeks. But Shanahan said it takes time to get back to speed after McCaffrey had almost no practice time for nine months. “Guys who miss offseasons and miss training camp, usually it takes them a little bit of time at the beginning of the year to get back into how they were the year before, let alone missing half the season also on top of that,” Shanahan said. “I think Christian’s doing a hell of a job. But to just think him coming back in Week 8 with not being able to do anything for the last nine months or whatever it is, and to think he’s just going to be in MVP form is a very unrealistic expectation.” NOTES: LB Dre Greenlaw took part in his first practice since tearing his Achilles tendon in the Super Bowl. Greenlaw will likely need a couple of weeks of practice before being able to play. ... LB Fred Warner said he has been dealing with a fracture in his ankle since Week 4 and is doing his best to manage the pain as he plays through it. ... CB Deommodore Lenoir didn't practice after banging knees on Sunday. His status for this week remains in question. ... DT Jordan Elliott (concussion), OL Aaron Banks (concussion) and LB Demetrius Flannigan-Fowles (knee) also didn't practice. AP NFL: https://apnews.com/hub/NFL��>�
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Trump Picks Keith Kellogg to Be Envoy to Ukraine and Russia

Microbio Co., Ltd. (4128) Announces Promising Results of "MS-20" in Combination with Keytruda for Stage IIIb/IV Non-Small Cell Lung Cancer

Luigi Nicholas Mangione, the suspect in the fatal shooting of a healthcare executive in New York City, apparently was living a charmed life: the grandson of a wealthy real estate developer, valedictorian of his elite Baltimore prep school and with degrees from one of the nation's top private universities. Friends at an exclusive co-living space at the edge of touristy Waikiki in Hawaii where the 26-year-old Mangione once lived widely considered him a “great guy,” and pictures on his social media accounts show a fit, smiling, handsome young man on beaches and at parties. Now, investigators in New York and Pennsylvania are working to piece together why Mangione may have diverged from this path to make the violent and radical decision to gun down UnitedHealthcare CEO Brian Thompson in a brazen attack on a Manhattan street. The killing sparked widespread discussions about corporate greed, unfairness in the medical insurance industry and even inspired folk-hero sentiment toward his killer. But Pennsylvania Gov. Josh Shapiro sharply refuted that perception after Mangione's arrest on Monday when a customer at a McDonald's restaurant in Pennsylvania spotted Mangione eating and noticed he resembled the shooting suspect in security-camera photos released by New York police. “In some dark corners, this killer is being hailed as a hero. Hear me on this, he is no hero,” Shapiro said. “The real hero in this story is the person who called 911 at McDonald’s this morning.” Mangione comes from a prominent Maryland family. His grandfather, Nick Mangione, who died in 2008, was a successful real estate developer. One of his best-known projects was Turf Valley Resort, a sprawling luxury retreat and conference center outside Baltimore that he purchased in 1978. The Mangione family also purchased Hayfields Country Club north of Baltimore in 1986. On Monday, Baltimore County police officers blocked off an entrance to the property, which public records link to Luigi Mangione’s parents. Reporters and photographers gathered outside the entrance. The father of 10 children, Nick Mangione prepared his five sons — including Luigi Mangione’s father, Louis Mangione — to help manage the family business, according to a 2003 Washington Post report. Nick Mangione had 37 grandchildren, including Luigi, according to the grandfather's obituary. Luigi Mangione’s grandparents donated to charities through the Mangione Family Foundation, according to a statement from Loyola University commemorating Nick Mangione’s wife’s death in 2023. They donated to various causes, including Catholic organizations, colleges and the arts. One of Luigi Mangione’s cousins is Republican Maryland state legislator Nino Mangione, a spokesman for the lawmaker’s office confirmed. “Our family is shocked and devastated by Luigi’s arrest,” Mangione’s family said in a statement posted on social media by Nino Mangione. “We offer our prayers to the family of Brian Thompson and we ask people to pray for all involved.” Mangione, who was valedictorian of his elite Maryland prep school, earned undergraduate and graduate degrees in computer science in 2020 from the University of Pennsylvania, a university spokesman told The Associated Press. He learned to code in high school and helped start a club at Penn for people interested in gaming and game design, according to a 2018 story in Penn Today, a campus publication. His social media posts suggest he belonged to the fraternity Phi Kappa Psi. They also show him taking part in a 2019 program at Stanford University, and in photos with family and friends at the Jersey Shore and in Hawaii, San Diego, Puerto Rico, and other destinations. The Gilman School, from which Mangione graduated in 2016, is one of Baltimore’s elite prep schools. The children of some of the city’s wealthiest and most prominent residents, including Orioles legend Cal Ripken Jr., have attended the school. Its alumni include sportswriter Frank Deford and former Arizona Gov. Fife Symington. In his valedictory speech, Luigi Mangione described his classmates’ “incredible courage to explore the unknown and try new things.” Mangione took a software programming internship after high school at Maryland-based video game studio Firaxis, where he fixed bugs on the hit strategy game Civilization 6, according to a LinkedIn profile. Firaxis' parent company, Take-Two Interactive, said it would not comment on former employees. He more recently worked at the car-buying website TrueCar, but has not worked there since 2023, the head of the Santa Monica, California-based company confirmed to the AP. From January to June 2022, Mangione lived at Surfbreak, a “co-living” space at the edge of touristy Waikiki in Honolulu. Like other residents of the shared penthouse catering to remote workers, Mangione underwent a background check, said Josiah Ryan, a spokesperson for owner and founder R.J. Martin. “Luigi was just widely considered to be a great guy. There were no complaints,” Ryan said. “There was no sign that might point to these alleged crimes they’re saying he committed.” At Surfbreak, Martin learned Mangione had severe back pain from childhood that interfered with many aspects of his life, including surfing, Ryan said. “He went surfing with R.J. once but it didn’t work out because of his back,” Ryan said, but noted that Mangione and Martin often went together to a rock-climbing gym. Mangione left Surfbreak to get surgery on the mainland, Ryan said, then later returned to Honolulu and rented an apartment. An image posted to a social media account linked to Mangione showed what appeared to be an X-ray of a metal rod and multiple screws inserted into someone's lower spine. Martin stopped hearing from Mangione six months to a year ago. An X account linked to Mangione includes recent posts about the negative impact of smartphones on children; healthy eating and exercise habits; psychological theories; and a quote from Indian philosopher Jiddu Krishnamurti about the dangers of becoming “well-adjusted to a profoundly sick society.” Mangione likely was motivated by his anger at what he called “parasitic” health insurance companies and a disdain for corporate greed, according to a law enforcement bulletin obtained by AP. He wrote that the U.S. has the most expensive healthcare system in the world and that the profits of major corporations continue to rise while “our life expectancy” does not, according to the bulletin, based on a review of the suspect’s handwritten notes and social media posts. He appeared to view the targeted killing of the UnitedHealthcare CEO as a symbolic takedown, asserting in his note that he is the “first to face it with such brutal honesty,” the bulletin said. Mangione called “Unabomber” Ted Kaczynski a “political revolutionary” and may have found inspiration from the man who carried out a series of bombings while railing against modern society and technology, the document said. Associated Press reporters Lea Skene in Baltimore; Jennifer Sinco Kelleher in Honolulu; Maryclaire Dale in Philadelphia; John Seewer in Toledo, Ohio; and Michael Kunzelman in Washington, D.C., contributed to this report.WASHINGTON (AP) — President-elect Donald Trump has assembled a team of medical contrarians and health care critics to fulfill an agenda aimed at remaking how the federal government oversees medicines, health programs and nutrition. On Tuesday night, Trump nominated Dr. Jay Bhattacharya to lead the National Institutes of Health, tapping an opponent of pandemic lockdowns and vaccine mandates to lead the nation's top medical research agency. He is the latest in a string of Trump nominees who were critics of COVID-19 health measures. Bhattacharya and the other nominees are expected to play pivotal roles in implementing Robert F. Kennedy Jr's sprawling “Make America Healthy Again,” agenda , which calls for removing thousands of additives from U.S. foods, rooting out conflicts of interest at agencies and incentivizing healthier foods in school lunches and other nutrition programs. Trump nominated Kennedy to head the Department of Health and Human Services , which oversees NIH and other federal health agencies. The new health priorities bear little resemblance to those of Trump’s first term, which focused on cutting regulations for food, drug and agriculture companies. “You’re hearing a very different tune as we head into this new Trump administration,” said Gabby Headrick, a nutrition researcher at George Washington University’s school of public health. “It’s important that we all proceed with caution and remember some of the public health losses we saw the first time.” Trump's nominees don't have experience running large bureaucratic agencies, but they know how to talk about health on TV . Centers for Medicare and Medicaid pick Dr. Mehmet Oz hosted a talk show for 13 years and is a well-known wellness and lifestyle influencer. The pick for the Food and Drug Administration, Dr. Marty Makary, and for surgeon general, Dr. Janette Nesheiwat, had been frequent Fox News contributors. Some of them have ties to Florida like many of Trump's other Cabinet nominees: Dave Weldon , the pick for the Centers for Disease Control and Prevention, represented the state in Congress for 14 years. Here's a look at how the nominees may carry out Kennedy's plans to “reorganize” agencies, which have an overall $1.7 trillion budget, employ 80,000 scientists, researchers, doctors and other officials: The National Institutes of Health, with a $48 billion budget, funds medical research through grants to scientists across the nation and conducts its own research. Bhattacharya, a health economist and physician at Stanford University, was one of three authors of the Great Barrington Declaration, an October 2020 letter maintaining that lockdowns were causing irreparable harm. The document — which came before the availability of COVID-19 vaccines — promoted “herd immunity,” the idea that people at low risk should live normally while building up immunity to COVID-19 through infection. Protection should focus instead on people at higher risk, the document said. “I think the lockdowns were the single biggest public health mistake,” Bhattacharya said in March 2021 during a panel discussion convened by Florida Gov. Ron DeSantis. The Great Barrington Declaration was embraced by some in the first Trump administration, even as it was widely denounced by disease experts. Then- NIH director Dr. Francis Collins called it dangerous and “not mainstream science.” His nomination would need to be approved by the Senate. Kennedy has said he would pause NIH's drug development and infectious disease research and shift its focus to chronic diseases. He also would like to keep NIH funding from researchers with conflicts of interest. In 2017, he said the agency wasn't doing enough research into the role of vaccines in autism — an idea that has long been debunked . The Atlanta-based CDC, with a $9.2 billion core budget, is charged with protecting Americans from disease outbreaks and other public health threats. Kennedy has long attacked vaccines and criticized the CDC, repeatedly alleging corruption at the agency. He said on a 2023 podcast that there is "no vaccine that is safe and effective,” and urged people to resist the CDC's guidelines about if and when kids should get vaccinated . The World Health Organization estimates that vaccines have saved more than 150 million lives over the past 50 years, and that 100 million of them were infants. Decades ago, Kennedy found common ground with Weldon , who served in the Army and worked as an internal medicine doctor before he represented a central Florida congressional district from 1995 to 2009. Starting in the early 2000s, Weldon had a prominent part in a debate about whether there was a relationship between a vaccine preservative called thimerosal and autism. He was a founding member of the Congressional Autism Caucus and tried to ban thimerosal from all vaccines. Since 2001, all vaccines manufactured for the U.S. market and routinely recommended for children 6 years or younger have contained no thimerosal or only trace amounts, with the exception of inactivated flu vaccine. Meanwhile, study after study found no evidence that thimerosal caused autism. Weldon's congressional voting record suggests he may go along with Republican efforts to downsize the CDC, including to eliminate the National Center for Injury Prevention and Control, which works on topics like drownings, drug overdoses and shooting deaths. Kennedy has been extremely critical of the FDA, which has 18,000 employees and is responsible for the safety and effectiveness of prescription drugs, vaccines and other medical products, as well as overseeing cosmetics, electronic cigarettes and most foods. Makary, Trump’s pick to run the FDA, is a professor at Johns Hopkins University, a trained surgeon and a cancer specialist. He is closely aligned with Kennedy on several topics . Makary has decried the overprescribing of drugs, the use of pesticides on foods and the influence of pharmaceutical and insurance companies over doctors and government regulators. Kennedy has suggested he'll clear out “entire” FDA departments and also recently threatened to fire FDA employees for “aggressive suppression” of a host of unsubstantiated products and therapies, including stem cells, raw milk , psychedelics and discredited COVID-era treatments like hydroxychloroquine. Makary's contrarian views during COVID-19 included questioning the need for COVID-19 vaccine boosters in young kids. The agency provides health care coverage for more than 160 million people through Medicaid, Medicare and the Affordable Care Act, and also sets Medicare payment rates for hospitals, doctors and other providers. With a $1.1 trillion budget and more than 6,000 employees, Oz has a massive agency to run if confirmed — and an agency that Kennedy hasn't talked about much. While Trump tried to scrap the Affordable Care Act in his first term, Kennedy has not taken aim at it yet. The Biden administration on Tuesday revealed a new plan to force Medicare and Medicaid to cover weight-loss drugs like Wegovy and Zepbound for many Americans who are obese. Kennedy has opposed the idea , saying government-sponsored insurance programs should instead expand coverage of healthier foods and gym memberships. Trump said during his campaign that he would protect Medicare, which provides insurance for older Americans. Oz has endorsed expanding Medicare Advantage — a privately run version of Medicare that is popular but also a source of widespread fraud . Kennedy doesn't appear to have said much publicly about what he'd like to see from the surgeon general. The nation's top doctor has little administrative power but can influence what counts as a public health danger and what to do about it — suggesting things like warning labels for products and issuing advisories. The current surgeon general, Vivek Murthy, declared gun violence as a public health crisis in June. Trump's pick, Nesheiwat, is employed as a New York City medical director with CityMD, a group of urgent care facilities. She also has appeared on Fox News and other TV shows, authored a book on the “transformative power of prayer” in her medical career and endorses a brand of vitamin supplements. Associated Press writers Mike Stobbe, Amanda Seitz, Carla K. Johnson, Matthew Perrone and Erica Hunzinger contributed to this report. The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

SHEPHERDSTOWN - After enrolling in a musical entrepreneurship class at the beginning of this semester at Shepherd University, four friends found themselves growing excited about their final project - creating a business plan for a hypothetical musical group. As they worked together toward this final goal, they realized that they wanted to take it a step further than their teacher, Kurtis Adams, interim dean of the College of Arts, Humanities and Social Sciences and director of jazz studies, had required. The students decided to actually create the musical group that their business plan was developed for between themselves. They then decided to end the semester with a performance or two as the new quartet, Unstrung. On Nov. 12, Unstrung performed together during Shepherd's Small Ensembles Recital in the Frank Center. They then performed a full-length concert this past Saturday on McMurran Hall's lawn. "In the class on entrepreneurship, we talked about how, with a performance degree, getting gigs is really hard when you're right out of college. Dr. Adams, which was the professor for the class, talked about how he came together with other musicians and made groups with them and recorded with them, and they made money off of coming together after finding that they couldn't get gigs on their own," said instrumental performance major Gabby Tedeschi, whose concentration is in clarinet. "That's was a big driving force behind our decision to form our own group." Although the quartet has no set plans for future performances, they hope to perform together again after graduation at venues around the D.C. metropolitan area. "We're all seniors in college right now, and we're all finishing up our performance degrees right now, so we probably will take a break from performing together next semester," Tedeschi said, mentioning two of the quartet's members will be performing their senior recitals in the spring semester. "But we definitely want to someday meet up again and perform together." Unstrung's saxophonist, Emily Ellmore, is double majoring in music performance and composition. She was particularly instrumental to the group's success, as she used her composition skills to arrange quartets for trumpet, clarinet, harp and saxophone out of two works by Joseph Haydn and Charles Ives, which were originally written for string quartets. "We wanted to specifically do string quartet music, because of our name, 'Unstrung,'" Ellmore said, as the group chuckled in response. While one of the instruments in the quartet does technically have strings, instrumental performance major Charity Meyer said her harp is not strung in the same way as the typical stringed instrument. "The harp's way of being strung is so entirely different from the way that violin or cello are strung," Meyer said. "That definitely made it a bit of a challenge for Emily." As the quartet smiled with joy at the completion of their concert, they expressed their delight in having been able to turn their final project into a reality. "Although this was for a class, it felt like we were doing this, because we wanted to, more than anything else," said instrumental performance major Levi Parker, whose concentration is in trumpet. "There was a lot of work that went into this, outside of the regular class expectations, but it was all worth it, to be able to do this together."

Musk’s government overhaul plan: 'Delete' bureau that returns billions to AmericansAgnico-Eagle Mines Ltd. stock rises Friday, outperforms market​Hackers have used new GodLoader malware exploiting the capabilities of the widely used Godot game engine to evade detection and infect over 17,000 systems in just three months. As Check Point Research found while investigating the attacks, threat actors can use this malware loader to target gamers across all major platforms, including Windows, macOS, Linux, Android, and iOS. It's also used to leverage Godot's flexibility and its GDScript scripting language capabilities to execute arbitrary code and bypass detection systems using the game engine .pck files, which package game assets, to embed harmful scripts. Once loaded, the maliciously crafted files trigger malicious code on the victims' devices, enabling attackers to steal credentials or download additional payloads, including the XMRig crypto miner. This miner malware's configuration was hosted on a private Pastebin file uploaded in May, which was visited 206,913 times throughout the campaign. "Since at least June 29, 2024, cybercriminals have been taking advantage of Godot Engine to execute crafted GDScript code which triggers malicious commands and delivers malware. This technique has remained undetected by most antivirus tools on VirusTotal, possibly infecting more than 17,000 machines in just a few months," according to Check Point . "Godot has a vibrant and growing community of developers who value its open-source nature and powerful capabilities. Over 2,700 developers contributed to the Godot gaming engine," while "on platforms like Discord, YouTube, and other social media platforms, the Godot engine has around 80,000 followers who stay updated on the latest news." ​The attackers delivered the GodLoader malware through the Stargazers Ghost Network , a malware Distribution-as-a-Service (DaaS) that masks its activities using seemingly legitimate GitHub repositories. Between September and October 2024, they used over 200 repositories controlled by over 225 Stargazer Ghost accounts to deploy the malware to targets' systems, exploiting potential victims' trust in open-source platforms and seemingly legitimate software repositories. Throughout the campaign, Check Point detected four separate attack waves against developers and gamers between September 12 and October 3, enticing them to download infected tools and games. While the security researchers only discovered GodLoader samples targeting Windows systems, they also developed GDScript proof-of-concept exploit code showing how easily the malware can be adapted to attack Linux and macOS systems. Stargazer Goblin , the threat actor behind the Stargazers Ghost Network DaaS platform used in these attacks, was first observed by Check Point promoting this malware distribution service on the dark web in June 2023. However, it has likely been active since at least August 2022, earning over $100,000 since this service was launched. The Stargazers Ghost Network uses over 3,000 GitHub "ghost" accounts to create networks of hundreds of repositories that can be used to deliver malware (mainly information stealers like RedLine, Lumma Stealer, Rhadamanthys, RisePro, and Atlantida Stealer) and star, fork, and subscribe to these malicious repos to push them to GitHub's trending section and increase their apparent legitimacy.

The US tech giant said it now supported 550,000 jobs in the UK through direct employment, its supply chain and the economy around its App Store – with app developers having earned nearly £9 billion since it launched in 2008. Apple said its engineering teams were carrying out critical work on the firm’s biggest services, including key technology within Apple Intelligence, the iPhone maker’s suite of generative AI-powered tools which are expected to launch in the UK for the first time this week. Elsewhere, the firm said its growing TV empire, spearheaded by its Apple TV+ streaming service and production arm, had also helped boost its investment in the UK with Apple TV+ production in this country tripling in the last two years, the company said. Chief executive Tim Cook said: “We’ve been serving customers in the UK for more than 40 years, and we’re proud of our deep connection with communities across this country. “We’re thrilled to be growing our Apple teams here, and to keep supporting the extraordinary innovators, creators, and entrepreneurs who are pushing the boundaries of technology in so many ways.” The Chancellor Rachel Reeves said companies such as Apple were “intrinsic” to the UK’s prosperity by boosting jobs. “This government is laser focused on creating the right conditions for growth to help put more money in people’s pockets. “That’s what underpins the Plan for Change and is what has driven £63 billion worth of inward investment in the UK through our first international investment summit. “Companies like Apple are intrinsic to the success of our nation’s prosperity – helping deliver jobs, innovative technology, and boost infrastructure.”