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Scientists identify brain cell type as master controller of urination December 3, 2024 eLife Researchers have identified a subset of brain cells in mice that act as the master regulators of urination. Facebook Twitter Pinterest LinkedIN Email Researchers have identified a subset of brain cells in mice that act as the master regulators of urination. The research, published today as a Reviewed Preprint in eLife , is described by editors as an important study with convincing data showing that estrogen receptor 1-expressing neurons (ESR1+) in the Barrington's nucleus of the mouse brain coordinate both bladder contraction and relaxation of the external urethral sphincter. Urination requires the coordinated function of two units of the lower urinary tract. The detrusor muscle of the bladder wall relaxes to allow the bladder to fill and empty, while the external sphincter opens when it's appropriate to allow urine to flow out, but otherwise keeps tightly shut. "Impairment of coordination between the bladder muscle and the sphincter leads to various urinary tract dysfunctions and can significantly degrade a person's quality of life," says first author Xing Li, Advanced Institute for Brain and Intelligence, School of Physical Science and Technology, Guangxi University, Nanning, China. "But although we know the individual nerve signalling pathways that control each of these urinary tract components, we don't know which brain areas ensure they cooperate at the right time." To explore this, the authors used state-of-the-art live cell imaging to study the activity of brain cells in anaesthetised and awake mice during urination. They focused on a brain region called the pontine micturition centre (PMC), otherwise known as the Barrington's nucleus, and compared the activity of different PMC nerve cell subtypes. In their first experiments, they measured the activity of the cells as the bladder empties by measuring changes in levels of calcium. This revealed that the electrical firing rate of a subset of PMC cells expressing estrogen receptors (PMC ESR1+ cells) was tightly linked to bladder emptying. When they combined this with monitoring bladder physiology, they found that it was not only the timing of PMC ESR1+ cell activity that correlated with bladder emptying, but the strength of cell electrical activity, too. Next, they tested what happened to urination if they blocked or triggered the PMC ESR1+ cells. They found that when PMC ESR1+ cell activity was blocked, the amount of urine the mice passed was significantly reduced and ongoing urination was suspended from the moment the cells were inactive. To understand the mechanism behind this, they measured the activity of the bladder muscle and sphincter. They discovered that both increase of bladder pressure and sphincter muscle bursting activity associated with bladder emptying both stopped when PMC ESR1+ cell activity was blocked during an ongoing voiding even. Similarly, when PMC ESR1+ cells were artificially activated using light, bladder emptying occurred 100% of the time. This suggests that PMC ESR1+ cells work as a reliable master switch that either initiates or suspends bladder emptying. To test whether PMC ESR1+ cells can influence bladder emptying independently of controlling the sphincter, they disconnected either the nerve carrying messages from the brain to the sphincter, or the nerve carrying messages from the brain to the bladder. They found that PMC ESR1+ cell control of the bladder was fully operational even when communication to the sphincter was blocked, and vice versa. This showed the cells could control the bladder and sphincter independently of one another, but the question remained: could they coordinate the action of the bladder muscle and sphincter together? That is, operate them in a controlled, perfectly timed manner, to trigger bladder emptying when appropriate? To explore this, they simultaneously recorded bladder pressure and electromyography measurements of sphincter activity. The timing of bladder pressure changes immediately before sphincter bursting activity was consistent for both spontaneous bladder emptying and emptying caused by activating the PMC ESR1+ cells, showing that these cells can coordinate the two steps in a precisely temporal sequence and controlled way. "Our study shows that a subset of cells in the Barrington's nucleus of the brain can initiate and suspend bladder emptying with 100% accuracy when needed, for example, to release only a small volume for landmarking by animals, or for a human to urinate into a small sample tube for a health check," concludes senior author Xiaowei Chen, Third Military Medical University, and Chongqing Institute for Brain and Intelligence, China. "While other cells will no doubt be involved in perfect urination control, our pinpointing of PMC ESR1+ cells' crucial role in bladder-sphincter coordination will aid the development of targeted therapies for treating urination dysfunction caused by brain or spinal cord injury or peripheral nerve damage." Story Source: Materials provided by eLife . Note: Content may be edited for style and length. Journal Reference : Cite This Page :777 jili games 。

Japan – Scientists develop new tech to turn sunlight, water into hydrogen fuel Japanese scientists have developed a new means of cracking water into hydrogen fuel using sunlight. Using a special photocatalyst, this new technology could help usher in cheaper, more abundant, and sustainable hydrogen fuel for various applications. Currently, most free hydrogen is derived from natural gas feedstocks, meaning moving away from fossil fuels for this greener option is not an option. However, this easily manufactured sunlight-powered method could prove pivotal if hydrogen is to become an alternative in the future. of Shinshu University, senior author of the article in Frontiers in Science explained. “However, many challenges remain,” he added.The basic principle behind the new process is to split water into oxygen and hydrogen. While it sounds simple, this is energy-intensive and needs a catalyst, in this case, special ones called photocatalysts. Hydrogen from water using light When exposed to light, these catalysts facilitate chemical reactions that break down water into constituent parts. The concept is not new, but most existing, so-called “one-step” ones are inefficient and have a meager solar-to-hydrogen energy conversion rate. Another more sophisticated also exists, and it is more efficient. In these systems, one photocatalyst generates hydrogen from water, while another produces oxygen. of Shinshu University, another study author said,The Japanese team chose this second “two-step” water-cracking process. “But by storing the energy of sunlight as the chemical energy of fuel materials, it is possible to use [it] anytime and anywhere,” he added. Domen and Hisatomi’s team produced a successful proof of concept by operating a 1,076 ft2 (100 m2) reactor for three years. This reactor even performed better in real-world sunlight than in laboratory conditions. said, Not just theory “Simulated standard sunlight uses a spectrum from a slightly high latitude region. Solar energy conversion efficiency could be higher in areas where natural sunlight has more short-wavelength components than simulated reference sunlight. However, currently, the efficiency under simulated standard sunlight is 1% at best, and it will not reach 5% efficiency under natural sunlight,” he added. forward and break that 5% barrier, the team says that more researchers need to develop more efficient and build larger experimental reactors. explained “If it is improved to a practical level, many researchers will work seriously on developing mass production technology, gas separation processes, and large-scale plant construction. This will also change how many people, including policymakers, think about solar energy conversion and accelerate the development of infrastructure, laws, and regulations related to solar fuels,” READ the latest news shaping the hydrogen market at Japan – Scientists develop new tech to turn sunlight, water into hydrogen fuel, Panasonic Installs an In-house Hydrogen based Renewable Energy Power Generation System in Its UK Factory Tokyo, Japan – Panasonic Corporation (Head office: Minato-ku, Tokyo; CEO: Masahiro Shinada; hereinafter... Improved catalyst turns harmful greenhouse gases into cleaner fuels, chemical feedstocks – hydrogen included A chemical reaction can convert two polluting greenhouse gases into valuable building blocks for cleaner... Panasonic Inaugurates Use of Panasonic HX to Symbolize an Energy Solution That Utilizes Hydrogen Panasonic establishes a marketing name to symbolize its hydrogen business upon installing a demonstration system in its...At this conference on AI Journey, Russian President Vladimir Putin announced the launch of BRICS-enhancing artificial intelligence and that he expected many following countries to join this alliance soon. “An Agency of seriousness will be the international Alliance of national associations and development institutions in artificial intelligence of States from BRICS and other interested countries; today, we will launch such an alliance at a conference, ‘Journey to the World of Artificial Intelligence,” the President said. “I expect new foreign participants, including my colleagues – the first persons of states, to join this event. The President has said that Russia is ready to facilitate and apply generative models across and beyond the Russian framework. “The algorithms of such systems, as I have already said, must be trusted, that is, understandable, open and unbiased, developed taking into account the cultural, national characteristics of each civilization with its history, identity, and traditions, which we in Russia treat with deep respect,” the President summed up. Reuters, President Vladimir Putin said on Wednesday that Russia would develop artificial intelligence with BRICS partners and other countries, in a bid to challenge the dominance of the United States in one of the most promising and crucial technologies of the 21st century.Dillon Gabriel's run at Oregon harkens back to the days of another Hawaii-born QB, Marcus MariotaLaura Woods shares 'too cute' present from Arsenal boss Mikel Arteta

SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of HelloFresh SE - HLFFF

Taking the witness stand on Thursday, Santa Clara Councilmember Suds Jain testified that he “assumed” Vice Mayor Anthony Becker gave the electric “Unsportsmanlike Conduct” report to a journalist before it was public — a slight deviation from testimony he gave to the criminal grand jury that indicted Becker last year. Jain said that Becker — one of his allies on the Santa Clara City Council since 2020 — had called him about two or three weeks before he was expected to testify in front of a criminal grand jury on March 29, 2023. During the phone call, Jain said that Becker admitted he had given the Santa Clara County civil grand jury report to Carolyn Schuk, an editor at the Silicon Valley Voice. Becker is currently on trial in Santa Clara County Superior Court in Morgan Hill for allegedly leaking the 2022 report — which chastised five members of the Santa Clara City Council for their relationship with San Francisco 49ers lobbyists — as well as felony perjury for allegedly lying about the leak under oath. The controversial report was supposed to be released publicly on Oct. 10, 2022, but appeared in several media outlets a few days prior. Rahul Chandhok, the 49ers’ former chief of communications, testified last week that Becker leaked him the report . During Jain’s March 29 testimony to the criminal grand jury, Deputy District Attorney Jason Malinsky asked the councilmember if Becker told him that he sent the report to a journalist “before it was public.” Jain confirmed that Becker had. But back in court on Thursday, Jain said he didn’t recall his prior testimony. “He told me that he had given the report to Carolyn Shuk,” Jain said. “I assumed it was during that period.” At one point, Malinsky showed Jain his prior testimony, to which he responded that he believed he was “confused.” The recently re-elected councilmember said that he wished Becker hadn’t told him. At the time, the two were discussing “how much stress he was under.” “I knew I had a subpoena, and it would have been better if he hadn’t told me,” he said. “It put me in a difficult position.” Jain testified that he didn’t ask his colleague any follow-up questions because he “did not want to know anymore.” When asked by a juror why Becker would have to give a journalist the report if it was already publicly available on the county’s website, Jain said “it’s possible that a reporter didn’t know where to find it. I don’t know.” Following Jain’s testimony, the prosecution played an audio recording of their interview with Becker on Dec. 28, 2022. Fernando Ramirez Jr., a criminalist with the Santa Clara County Crime Laboratory, testified as an expert witness the day prior that a forensic analysis of Becker’s phone showed that he had uninstalled Signal — the encrypted messaging app he allegedly used to leak the report — on Dec. 28 at 9:09 a.m. Becker’s meeting with Malinsky and Ben Holt, a criminal investigator with the DA’s office, commenced at 9:17 a.m. — less than nine minutes after data showed he deleted the app. In a snippet of the interview that was played for the jury, Becker said he hadn’t communicated with anyone from the 49ers “for a while.” He told Malinsky and Holt that he only used his phone’s native texting app to communicate with Chandhok, his main contact at the 49ers. Becker said he didn’t use Signal. But when asked by Malinsky if he used it in the past, he questioned why he was being asked so much about Chandhok. “Do I need a lawyer, because this is starting to get really inquisitive about my relationship with the 49ers?” Becker said. The vice mayor eventually admitted to having used the app in the past with one of his campaign staffers. When Malinsky asked Becker if he had used it to communicate with Chandhok, he said he didn’t know. “I don’t know why this is so important if we had conversations on Signal,” he said. Becker also denied leaking the grand jury report during the interview, and said he deleted Signal off of his phone “some time after the election.” The DA’s office served Becker with a search warrant following the interview.NEW YORK , Dec. 27, 2024 /PRNewswire/ -- Pomerantz LLP announces that a class action lawsuit has been filed against Zeta Global Holdings Corp. ("Zeta" or the "Company") (NYSE: ZETA ). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, (or 888.4-POMLAW), toll-free, Ext. 7980. Those who inquire by e-mail are encouraged to include their mailing address, telephone number, and the number of shares purchased. The class action concerns whether Zeta and certain of its officers and/or directors have engaged in securities fraud or other unlawful business practices. You have until January 21, 2025 , to ask the Court to appoint you as Lead Plaintiff for the class if you are a shareholder who purchased or otherwise acquired Zeta securities during the Class Period. A copy of the Complaint can be obtained a t www.pomerantzlaw.com . [Click here for information about joining the class action] On November 13, 2024 , market research group Culper Research published a report entitled "Zeta Global Holdings Corp (ZETA): Shams, Scams, and Spam." The report alleged that the "integrity of the Company's data collection and reported financials" is severely undermined by two factors. First, the report alleged that "Zeta has formed 'two-way' contracts with third party consent farms wherein the Company simultaneously acts as both a supplier and a buyer of consumer data," allowing the Company to "flatter reported revenue growth" and indicating possible "round-tripping" of revenue. Second, the report alleged that Zeta's collects the majority of its customer data from a network of "sham websites that hoodwink millions of consumers each month into handing their data over to Zeta under false pretenses." For example, the report alleged the Company and its subsidiaries operate a number of fake job boards which are designed to trick individuals into submitting personal data under the pretense of job applications. The report further alleged that the Company's "most valuable data" comes from these predatory websites, dubbed consent farms, which are "responsible for almost the entirety of the Company's growth." On this news, the Company's stock price fell $10.46 per share, or 37.07%, to close at $17.76 per share on November 13, 2024 . Pomerantz LLP, with offices in New York , Chicago , Los Angeles , London , Paris , and Tel Aviv , is acknowledged as one of the premier firms in the areas of corporate, securities, and antitrust class litigation. Founded by the late Abraham L. Pomerantz , known as the dean of the class action bar, Pomerantz pioneered the field of securities class actions. Today, more than 85 years later, Pomerantz continues in the tradition he established, fighting for the rights of the victims of securities fraud , breaches of fiduciary duty, and corporate misconduct. The Firm has recovered billions of dollars in damages awards on behalf of class members. See www.pomlaw.com . Attorney advertising. Prior results do not guarantee similar outcomes. CONTACT: Danielle Peyton Pomerantz LLP [email protected] 646-581-9980 ext. 7980 SOURCE Pomerantz LLPPep Guardiola: If I can’t reverse Manchester City slide then I have to go

FBI Director Wray says he intends to resign at the end of Biden's term in JanuaryGophers soccer team literally dancing its way into the NCAA tournament second round

Games: The Quad City Storm (5-10-1-1, 12 points) return home to host the Pensacola Ice Flyers (4-12-1-0, 9 points) in a meeting of the two teams at the bottom of the SPHL standings. Puck drop both evenings at Vibrant Arena at The Mark is scheduled for 7:10 p.m. Promotions: There are events scheduled for both nights this weekend. Friday is Scouts Night with the Storm wearing Mossy Oak Camo jerseys. Proceeds from the jersey auction benefit Illowa Scout Council. Special scout ticket offers and patches are available through Fintan (fintan@quadcitystorm.com). There is also a Scout Sleepover on the ice available with select ticket packages. Saturday, the team will recognize Mascot Mania and Radar’s Glow in the Dark Birthday, which features mascots from the entire region at Vibrant Arena to celebrate and entertain. The first 1,000 kids ages 12 and younger receive a replica jersey, courtesy of Tyson. The action on the ice starts with a laser show and, for the first time ever, the team will be wearing glow in the dark jerseys that will be auctioned postgame. People are also reading... History: This is the first meeting this season between the two clubs. Last season, QC was 4-1-0-0 against the Ice Flyers and the Storm are 8-2-2-1 over Pensacola the last five years. Familiar faces, different places: In a unique twist, QC and Pensacola were partners in a pair of trades this week. QC sent LW Alex Laplante (2 goals, 2 assists, 4 points in 15 games with a -7 plus/minus) and the rights to centerman Matt Ustaski (0 goals, 2 assists, 2 points in 5 games with a -2 rating) to the Ice Flyers in return for future considerations. Ustaski subsequently took a call-up to the ECHL Orlando Solar Bears and is not on the Pensacola active roster. Former QC netminder Kevin Resop is also on Pensacola’s roster, that numbered 17 as of Thursday. Game notes: Both of these teams continue to re-work their rosters. Pensacola has made 10 moves already this month, including losing centermen Greg Smith (1 goal, 9 assists, 10 points in 17 games with a -4 rating) and Cameron Cook (6-5-11, -11 plus/minus) to ECHL call-ups. Smith went to Adirondack and Cook to Reading. ... Pensacola is 0-2 this month having lost at Birmingham and to Macon last weekend. ... QC has not won a game in its last five starts. The Storm are coming in off a three-game weekend in Fayetteville in which they lost all three games by 4-3 scores. The opener was a shootout loss in which QC gained a point in the standings. ... Pensacola’s top scorer is former Peoria Riverman Cayden Cahill (4-6-10). ... QC has a pair of 20-point scorers in Leif Mattson (11-11-22) and Weiland Parrish (4-16-20). ... Pensacola is being outscored 66-41 this season and QC is being outscored 68-47. Those are the top two goals-against numbers in the league and the only ones over 60. ... Pensacola’s 41 goals are tied with Macon for the fewest in the league. — compiled by Tom Johnston Mattson Mattson Get in the game with our Prep Sports Newsletter Sent weekly directly to your inbox! sports writer/golf editor {{description}} Email notifications are only sent once a day, and only if there are new matching items.Share this Story : Housing Design Awards: An air of celebration and gratitude Copy Link Email X Reddit Pinterest LinkedIn Tumblr Breadcrumb Trail Links Life Homes Housing Design Awards: An air of celebration and gratitude Author of the article: Anita Murray, Anita Murray Published Nov 21, 2024 • Last updated 51 minutes ago • 6 minute read Join the conversation You can save this article by registering for free here . Or sign-in if you have an account. RND Construction was the top winner with seven trophies, including custom builder of the year and a custom home category for this home with Andre Godin Design. Photo by Gordon King Photography Reviews and recommendations are unbiased and products are independently selected. Postmedia may earn an affiliate commission from purchases made through links on this page. Article content It was a special night for Ottawa’s housing industry Nov. 2 as excellence in design was celebrated at the annual Housing Design Awards in record fashion. Organized by the Greater Ottawa Home Builders’ Association, the awards gala, now in its 41 st year, is one of the largest events of its kind in the city. A record 760 guests gathered at the Rogers Centre Ottawa (formerly the Shaw Centre), which was decked out in a theme of urban graffiti, complete with on-site artists creating works for auction, break dancers, record spinners and an Airstream RV serving signature drinks. Advertisement 2 Story continues below This advertisement has not loaded yet, but your article continues below. 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Activate your Online Access Now Article content Hobin Architecture claimed five awards, including two for an infill development near the Experimental Farm called Peridot. Photo by Riley Snelling Photography Trophies were awarded to area designers, architects, builders, renovators and suppliers in 54 categories ranging from kitchens and bathrooms to production and custom homes, renovations, green innovation, design details and more. In all, there were 232 finalists (another record) from 369 entries (yet another record). “Not only did we have a record number of entries and companies participating, but the quality of entries continues to climb even further, with our members striving to raise the bar even more each year,” says Linda Oliveri Blanchard, who chairs the awards committee. Ardington + Associates Design won five trophies, including one for this home with Maple Leaf Custom Homes and Cedar Ridge Designs & Custom Cabinetry. Photo by Kevin Belanger Photography Entries were judged by 12 industry experts from across the country, who each had certain categories to evaluate in blind judging. Laurysen Kitchens won five awards for a mix of kitchen and bathroom categories, including this one with Sonya Kinkade Design. Photo by JVL Photography “Overall, I was very impressed with the superior quality, the forward thinking, the beauty of these submissions,” says designer Benjamin John Ouellette of BJOID Inc., who judged the kitchen and bath categories. “Greater Ottawa has absolutely phenomenal talent.” Minto Communities was named production builder of the year, along with winning three other awards for the 2023 dream home in the CHEO lottery with Tanya Collins Design. Photo by Gordon King Photography Many of the trends or recurring elements that we saw in last year’s awards continued or were amplified this year. Arches, texture, wall treatments and wood were all popular, as they were last year. Joining them this year were moody bathrooms and the use of rich, saturated colour everywhere. Advertisement 3 Story continues below This advertisement has not loaded yet, but your article continues below. Article content Shean Architects claimed designer of the year from a crowded field of 12 entrants, along with winning two other categories. Photo by Scott Norsworthy photograph Big winners Leading the pack was RND Construction, which took home seven trophies ranging from custom homes and kitchens to green innovation and one of the prestige categories — custom builder of the year, a category that RND has won repeatedly, including for the last three years in a row. “It’s always a thrill to win,” RND owner Roy Nandram said the morning after the gala. He then added: “We need to think about the people who help us win an award: our staff or subtrades; our architects and designers we work with; and, more importantly, we have amazing clients.” Amsted Design-Build won three awards, including being named renovator of the year for a record 11th time. Amsted was also named Ontario renovator of the year earlier this fall. Photo by Gordon King Photography Following closely behind RND was a trio of companies with five wins each: Hobin Architecture, Laurysen Kitchens and Cedar Ridge Designs & Custom Cabinetry. Other prestige category winners included Shean Architects, which was named designer of the year among a crowded field of 12 entrants, and Amsted Design-Build, which reclaimed the renovator of the year award for a record 11 th time. Amsted was also named provincial renovator of the year at this fall’s Awards of Distinction put on by the Ontario Home Builders’ Association. Advertisement 4 Story continues below This advertisement has not loaded yet, but your article continues below. Article content For Amsted owner Steve Barkhouse, the overwhelming feeling was gratitude. “Grateful to see a record turnout to the event and a record number of fantastic submissions. Grateful to be pushed harder every year by our strong competition.” The All Things Home People’s Choice Award went to Modello Homes for a custom bungalow home that’s a blend of modern farmhouse and contemporary. Photo by Flex Media & Photography Other notable wins Minto Communities and Tanya Collins Design scooped up an impressive three trophies for one home — the grand prize home in last year’s CHEO Dream of a Lifetime lottery. A prime example of design infused with rich colour, the home was decorated with a palette of deep green, blue, burgundy and caramel. Collins won a fourth award for best home office and Minto also captured a fourth, for production builder of the year, a prestige award the builder last won in 2022. The final prestige category was the coveted All Things Home People’s Choice Award, the only trophy that is determined by public vote. This year’s award went to custom builder Modello Homes for a sophisticated modern farmhouse bungalow loft in an estate subdivision. PLOTNONPLOT Architecture teamed with Crossford Construction to win three awards of their own for one home, dubbed the Warren. The quirky yet sophisticated custom urban home took its cue from a rabbit’s lair, with the main living level partially embedded into the ground and boasting eye-catching round windows scattered throughout. The project won its custom home category and for its kitchen and primary ensuite. Advertisement 5 Story continues below This advertisement has not loaded yet, but your article continues below. Article content And Claridge Homes won four trophies, two for its Sussex model and one each for its Wentworth and Shinnecock models, all at River’s Edge in Riverside South. The homes opened earlier this year. Crossford Construction won four awards, including three with PLOTNONPLOT Architecture for a custom home dubbed the Warren. Photo by Kevin Belanger Photography The winners Production home, attached, 2,000 sq. ft. or less Claridge Homes, the Sussex Production home, attached, 2,001 sq. ft. or more Claridge Homes, the Wentworth Production home, single detached, under $950,000 Claridge Homes, the Shinnecock Hills Production home, single detached, $950,001 – $1,200,000 Mackie Homes, the Trenton Production home, single detached, $1,200,001 and over Hobin Architecture, the Beckett New community, underway BLD Homes, McEwen’s Mill New community, built Hobin Architecture, Peridot Apartment, condo or rental Uniform Urban Developments with Hobin Architecture and 2H Interior Design, Echo Condo or rental apartment suite, 801 sq. ft. or more Campanale with Raywal Cabinets, Urban Terraces at Longfields Square II Custom home, 3,000 sq. ft. or less Ardington + Associates Design with Maple Leaf Custom Homes and Cedar Ridge Designs & Custom Cabinetry Advertisement 6 Story continues below This advertisement has not loaded yet, but your article continues below. Article content Custom home, 3,001 sq. ft. or more Nowacki Homes Custom urban home, 2,800 sq. ft. or less PLOTNONPLOT Architecture with Crossford Construction Custom urban home, 2,800 – 3,800 sq. ft. RND Construction with Andre Godin Design Custom urban home, 3,800 sq. ft. or more Linebox Studio with Sanchez Homes Custom urban home, semi-detached RJH Architecture + Planning with Haslett Construction Production kitchen, 200 sq. ft. or less Laurysen Kitchens with Urbandale Construction Production kitchen, 201 – 250 sq. ft. Claridge Homes, the Sussex Production kitchen, 251 sq. ft. or more Minto Communities with Tanya Collins Design and Laurysen Kitchens, the Equestrian Custom kitchen, 175 sq. ft. or less, traditional Gordon Weima Design Builder Custom kitchen, 175 sq. ft. or less, contemporary PLOTNONPLOT Architecture with Crossford Construction Custom kitchen, 176 – 250 sq. ft., traditional West of Main with Urban Quarry Custom kitchen, 176 – 250 sq. ft., contemporary The Cabinet Connection Custom kitchen, 251 sq. ft. or more, traditional, $100,000 and under Sonya Kinkade Design with Laurysen Kitchens Advertisement 7 Story continues below This advertisement has not loaded yet, but your article continues below. Article content Custom kitchen, 251 sq. ft. or more, contemporary, $100,000 and under Simmonds Architecture with RND Construction and Cedar Ridge Designs & Custom Cabinetry Custom kitchen, 251 sq. ft. or more, traditional, $100,001 and over – John Laurysen Memorial Trophy West of Main with Urban Quarry Custom kitchen, 251 sq. ft. or more, contemporary, $100,001 and over RND Construction with Cedar Ridge Designs & Custom Cabinetry Production bathroom Minto Communities with Tanya Collins Design and Laurysen Kitchens, the Equestrian Custom bathroom, 100 sq. ft. or less, traditional Nathan Kyle Studio Custom bathroom, 100 sq. ft. or less, contemporary PLOTNONPLOT Architecture with Crossford Construction Custom bathroom, 101 sq. ft. or more, traditional West of Main with Urban Quarry and Cedar Ridge Designs & Custom Cabinetry Custom bathroom, 101 sq. ft. or more, contemporary Laurysen Kitchens with Peridot Design & Build Bathroom – powder room RND Construction with Cedar Ridge Designs & Custom Cabinetry Renovation under $150,000 Amsted Design-Build Renovation $150,001 – $250,000 Suite Spot Design with To Do-Done Advertisement 8 Story continues below This advertisement has not loaded yet, but your article continues below. Article content Renovation $250,001 – $400,000 Terra Nova Building Corp. Renovation $400,001 – $600,000 Amsted Design-Build Renovation $600,001 – $750,000 Shean Architects Renovation $750,001 – $1,000,000 Simmonds Architecture with Casa Verde Construction Renovation $1,000,001 and over Casa Verde Construction Basement renovation Suite Spot Design with To Do-Done Housing details Shean Architects with Cada Construction Any room in the house Hobin Architecture with Cada Construction Best home office Tanya Collins Design Exterior details Nowacki Homes Exterior living space Simmonds Architecture with RND Construction Alternative enclosed space Crossford Construction Anywhere in the world Hobin Architecture with 2H Interior Design Innovation award – production home of the year Minto Communities with Tanya Collins Design and Agrodrain Systems Limited, the Equestrian Innovation award – custom home of the year RND Construction Custom builder of the year RND Construction Designer of the year Shean Architects Production builder of the year Minto Communities Renovator of the year Amsted Design-Build All Things Home People’s Choice Award Modello Homes Article content Share this article in your social network Share this Story : Housing Design Awards: An air of celebration and gratitude Copy Link Email X Reddit Pinterest LinkedIn Tumblr Comments You must be logged in to join the discussion or read more comments. Create an Account Sign in Join the Conversation Postmedia is committed to maintaining a lively but civil forum for discussion. Please keep comments relevant and respectful. Comments may take up to an hour to appear on the site. You will receive an email if there is a reply to your comment, an update to a thread you follow or if a user you follow comments. Visit our Community Guidelines for more information. Trending 'Critical' watermain break prompts no-dig order in Ottawa Local News Special forces tracked former soldier’s social media, shared private info without consent Defence Watch You'll never guess which Ottawa restaurant made OpenTable's Top 100 list Local News DND tried to block veteran from requesting government records Defence Watch PBO 'not holding' his breath over public service layoffs as personnel spending still on the rise Public Service Read Next Latest National Stories Featured Local SavingsDillon Gabriel's run at Oregon harkens back to the days of another Hawaii-born QB, Marcus Mariota