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SAN JOSE, Calif., Nov. 27, 2024 (GLOBE NEWSWIRE) -- Nutanix , Inc. NTNX , a leader in hybrid multicloud computing, today announced that its management will present at the following upcoming financial community event: Barclays 22 nd Annual Global Technology Conference Thursday, December 12, 2024 10:25 a.m. PST; 1:25 p.m. EST A live webcast and replay of the presentation will be accessible on the Nutanix Investor Relations website at ir.nutanix.com About Nutanix Nutanix is a global leader in cloud software, offering organizations a single platform for running applications and managing data, anywhere. With Nutanix, companies can reduce complexity and simplify operations, freeing them to focus on their business outcomes. Building on its legacy as the pioneer of hyperconverged infrastructure, Nutanix is trusted by companies worldwide to power hybrid multicloud environments consistently, simply, and cost-effectively. Learn more at www.nutanix.com or follow us on social media @nutanix. © 2024 Nutanix, Inc. All rights reserved. Nutanix, the Nutanix logo, and all Nutanix product and service names mentioned herein are registered trademarks or unregistered trademarks of Nutanix, Inc. in the United States and other countries. Other brand names and marks mentioned herein are for identification purposes only and may be the trademarks of their respective holder(s). I nvestor Contact Richard Valera ir@nutanix.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
A high-speed passenger train collided with a fire engine at a crossing on Saturday in Florida, injuring three firefighters and at least a dozen train passengers, authorities said. The crash happened at 10.45am in crowded downtown Delray Beach, multiple news outlets reported. The Brightline train was stopped on the tracks, its front destroyed, about a block away from the Delray Beach fire rescue truck, its ladder ripped off and strewn in the grass several yards away, The Sun-Sentinel newspaper reported. The Delray Beach Fire Rescue said in a social media post that three Delray Beach firefighters were in stable condition at a hospital. Palm Beach County Fire Rescue took 12 people from the train to the hospital with minor injuries. Emmanuel Amaral rushed to the scene on his golf cart after hearing a loud crash and screeching train brakes from where he was having breakfast a couple of blocks away. He saw firefighters climbing out of the window of their damaged truck and pulling injured colleagues away from the tracks. One of their helmets came to rest several hundred feet away from the crash. “The front of that train is completely smashed, and there was even some of the parts to the fire truck stuck in the front of the train, but it split the car right in half. It split the fire truck right in half, and the debris was everywhere,” Mr Amaral said. Brightline officials did not immediately comment on the crash. A spokesperson for the National Transportation Safety Board said it was still gathering information about the crash and had not decided yet whether it will investigate. The NTSB is already investigating two crashes involving Brightline’s high-speed trains that killed three people early this year at the same crossing along the railroad’s route between Miami and Orlando. More than 100 people have died after being hit by trains since Brightline began operations in July 2017 – giving the railroad the worst death rate in the United States. But most of those deaths have been either suicides, pedestrians who tried to run across the tracks ahead of a train or drivers who went around crossing gates instead of waiting for a train to pass. Brightline has not been found to be at fault in those previous deaths. We do not moderate comments, but we expect readers to adhere to certain rules in the interests of open and accountable debate.BERWYN, Pa.--(BUSINESS WIRE)--Nov 21, 2024-- Virpax Pharmaceuticals, Inc. (Nasdaq: VRPX) (“Virpax” or the “Company”) , a company specializing in developing pharmaceutical products for pain management, announced that it has been granted an extension of its cooperative research and development agreement with the National Center for Advancing Translational Sciences (NCATS), an institute/center of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. This collaboration is for the continued development of Virpax’s product candidate, NES100, an intranasal peptide, for the management of acute and chronic non-cancer pain. NES100 is an enkephalin drug product based on a type of nanotechnology delivery approach. Enkephalin is a naturally occurring (endogenous) peptide that is not easily administered in its original form. We believe that the nanotechnology may enable and enhance the delivery of this metabolically labile peptide drug into the brain. NES100 is the first investigational product formulation delivered via the nasal route with the potential to enhance enkephalin transport to the brain. NES100 uses a preassembled device and cartridge to propel the enkephalin formulation through the nose to the brain by flowing along the olfactory nerve pathway. The Molecular Envelope Technology (MET) is designed to protect and help carry the drug to the brain with the goal of promptly suppressing pain by binding to the delta opioid receptors. NES100 has demonstrated analgesic potential in animal models without the development of opioid tolerance, withdrawal, respiratory depression, euphoria, or addiction associated with use of opioids. Jatinder Dhaliwal, Chief Executive Officer of Virpax, commented, "We are excited that this collaboration has been extended with NCATS and the NIH Helping to End Addiction Long-term (HEAL) initiative as we believe that it may help Virpax develop an effective and safe alternative to conventional opioids used by patients to manage acute and chronic pain. We believe that the NIH/NCATS collaborative agreement will enable our team to maintain momentum in both our pre-clinical and clinical development strategies." About Virpax Pharmaceuticals Virpax is developing branded, non-addictive pain management products candidates using its proprietary technologies to optimize and target drug delivery. Virpax is initially seeking FDA approval for two prescription drug candidates that employ two different patented drug delivery platforms. ProbudurTM is a single injection liposomal bupivacaine formulation being developed to manage post-operative pain and EnveltaTM is an intranasal molecular envelope enkephalin formulation being developed to manage acute and chronic pain, including pain associated with cancer. Virpax is also using its intranasal Molecular Envelope Technology (MET) to develop one other prescription product candidate, NobrXiolTM, which is being developed for the nasal delivery of a pharmaceutical-grade cannabidiol (CBD) for the management of rare pediatric epilepsy. Virpax has competitive cooperative research and development agreements (CRADAs) for two of its prescription drug candidates, one with the National Institutes of Health (NIH) and one with the Department of Defense (DOD). Virpax is also seeking partners for two nonprescription product candidates: AnQlar, which is being developed to inhibit viral replication caused by influenza or SARS-CoV-2, and EpoladermTM, which is a topical diclofenac spray film formulation being developed to manage pain associated with osteoarthritis. For more information, please visit https://www.virpaxpharma.com .and follow us on Twitter, LinkedIn and YouTube. Forward-Looking Statements This press release contains certain forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995, as amended, including those described below. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions. These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events and involve known and unknown risks, uncertainties, and other factors, including the additional capital which will be necessary to complete studies and clinical trials that the Company plans to initiate and other factors listed under “Risk Factors” in the Company’s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q that the Company has filed with the U.S. Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. View source version on businesswire.com : https://www.businesswire.com/news/home/20241121242163/en/ CONTACT: Investor Contact: info@virpaxpharma.com KEYWORD: PENNSYLVANIA UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: BIOTECHNOLOGY MEDICAL DEVICES HEALTH PHARMACEUTICAL MEDICAL SUPPLIES SOURCE: Virpax Pharmaceuticals, Inc. Copyright Business Wire 2024. PUB: 11/21/2024 04:05 PM/DISC: 11/21/2024 04:06 PM http://www.businesswire.com/news/home/20241121242163/en
With Apple Intelligence , Apple is aiming to make Siri smarter than ever before. The personal assistant is going to be able to learn more about you, do more in apps, and hand over the reins to a smarter virtual assistant when needed. Some new Siri features are available now, while some won't be coming until 2025. This guide highlights everything that's new with Siri thanks to Apple Intelligence. Updated Siri Design Siri has a refreshed design on devices that support Apple Intelligence. Rather than the small wavelength that used to show when activating Siri, there's now a pink/purple/blue/orange variegated glow that wraps around the entire iPhone , with the colors shifting as Siri listens to a command. Better Language Understanding Siri can better understand conversational language and requests, so if you stumble over your words or change your mind mid-sentence, Siri can still follow what you're saying. Siri is also able to maintain context between requests, so you can refer to something in a previous request, and Siri will understand what you're talking about. So if you use Siri to create a calendar event, you can then just ask "What will the weather be like there?" and Siri knows where "there" is. Improved Voice Siri has a new, more natural sounding voice. Type to Siri There is a built-in Type to Siri feature so you don't need to speak to Siri to interact with the personal assistant. To use it, double tap on the bottom of the iPhone or iPad to bring up a text bar, and then from there, just type in your request. Type to Siri can be used in the same way as speaking to Siri, and Siri is able to provide information without speaking aloud. It is a useful feature for public situations where you're not able to speak and do not want to have Siri speaking back to you. Siri on the Mac While this guide focuses on the iPhone and the iPad, the new, smarter Siri is also available on the Mac. Type to Siri can be enabled in the Settings app, and it can be assigned to a shortcut, such as pressing the Command button twice. Apple Product Knowledge Apple taught Siri about all of its products, so if you want to know how to use a feature or how to complete a task, you can ask Siri for help. Siri can provide step-by-step directions on using iPhone, iPad, and Mac features. ChatGPT Integration (iOS 18.2) In iOS 18.2, ChatGPT integration is available with Siri. If a user asks something that Siri is not capable of handling, ChatGPT can provide a response instead, so long as the user gives permission. Siri can tap into ChatGPT, and then relay ChatGPT's response with no need to switch apps or use other tools. The Siri ChatGPT integration can essentially be used to do anything you can do with the ChatGPT app or ChatGPT on the web, it's simply an easier way to get to ChatGPT. Object Identification For anything on your screen, such as an image, you can ask Siri a question about it. If you have a photo of a plant, for example, asking "What is this?" will prompt Siri to send a screenshot over to ChatGPT, and ChatGPT will attempt to provide context. This works with images on the web, your photos, the something you're viewing through the Camera app, text, and more. ChatGPT can be used to describe a scene, which is useful for people who might have issues with sight. Opening the Camera app, activating Siri, and asking "What is this?" will provide a detailed description of whatever is in front of you. The option to send images to ChatGPT from screenshots is distinct from the Siri onscreen awareness feature that Apple plans to implement in the future. Info From Documents For emails, documents, PDFs, and more, ChatGPT can provide a summary. When you ask "Can you summarize this?" Siri will send a screenshot or the entire document, which includes full PDFs. It's a useful feature for getting a quick overview of the content of a long document. For long PDFs or documents, you'll want to tap on the arrows to make sure the full document is sent to ChatGPT rather than just a screenshot. Rather than asking for a summary, you can instead ask a specific question about a document. If you're looking at an insurance policy, you can ask "What are the limits of this policy?" or "What are the exclusions?" to get more tailored information. Checking Spelling and Grammar If you've written an email, rather than selecting it and using Writing Tools to check it for spelling and grammar errors, you can ask Siri to take a look, and Siri will send a screenshot to ChatGPT. "Can you look this over for errors?" works as a command for this feature. ChatGPT can also be used for rewriting and refining what you've written, but note that this is not the same as Apple's own Writing Tools. Generating Text and Images ChatGPT can generate text from scratch based on prompts that it is given. You can, for example, ask Siri to ask ChatGPT to write a poem or compose a polite letter to a friend, and ChatGPT will create something from scratch. Some sample requests you can use: If you have ChatGPT write something for you, you can tap on the copy icon to copy it to the clipboard to paste it into Notes, Messages, a document, or an email. You can also create images. Using the Dall-E 3 engine, ChatGPT can make realistic AI-generated images, something that can't be done with Apple Intelligence. For image requests, it's easiest to tell Siri to "Tell ChatGPT to make an image of [thing you want an image of]," because if you just ask Siri to make an image or generate an image, it will often bring up web images. Answering Questions One of the best use cases for ChatGPT through Siri is getting answers for queries that are just a bit too complex for Siri. Questions that Siri can't handle will be handed over to ChatGPT with your permission, but you can also force Siri to use ChatGPT instead of the internal Siri engine by amending questions with "Ask ChatGPT." For example, a question about what battery an Xbox controller uses will source Wikipedia and not ChatGPT, but specifically "Ask ChatGPT what battery an Xbox controller uses" will prompt Siri to present the question to ChatGPT. ChatGPT's answers can sometimes be more informative. Asking Siri how to replace eggs in a recipe just gives you alternatives, but ChatGPT's answer for the same question provides the amount of an ingredient you might want to add to equate to an egg. Some example queries that Siri will automatically consult ChatGPT on: Other Things You Can Ask ChatGPT To Do While Siri can do all of these things with ChatGPT's help, the lack of continuity with the Siri version of ChatGPT makes it difficult to complete tasks that are not one-off requests. Creating a meal plan, for example, works better with the actual ChatGPT interface because you can have more of a conversation rather than relying on a single request. ChatGPT Settings and Privacy ChatGPT integration has to be turned on, and after that, each request requires user permission. There is an option to turn off the extra permission by toggling off the "Confirm ChatGPT Requests" option. The toggle can be accessed by opening up the Settings app, choosing Apple Intelligence, and then tapping on ChatGPT. With the feature disabled, Siri will not ask each time before sending information to ChatGPT. Siri will, however, always ask permission before sending a file to ChatGPT even with the confirm requests feature turned off. As for privacy, no login is required to use ChatGPT, and neither Apple nor OpenAI log your requests. But if you sign in with a paid account, ChatGPT can keep a copy of requests. ChatGPT - Free vs. Paid ChatGPT integration includes a limited number of requests that use ChatGPT-4o, the latest version of ChatGPT, for free. After those are used up, ChatGPT integration uses 4o Mini, which is less advanced and takes up less resources. ChatGPT Plus subscribers get more ChatGPT-4o requests. ChatGPT Plus is priced at $20 per month, and iPhone users who don't already have ChatGPT Plus can sign up right from the Apple Intelligence section of the Settings app. Apple users essentially have access to ChatGPT's basic plan, so requests that use advanced capabilities reset every 24 hours. With this plan, two images per day can be generated. ChatGPT vs. Apple Intelligence There is overlap between what's possible with Apple Intelligence and what you can do with ChatGPT integration, but there are some distinctions. Apple Intelligence has Writing Tools for rewriting and editing what you've already written, but ChatGPT can write content from scratch. Image Playground , Image Wand , and Genmoji allow you to generate images, but Apple Intelligence won't generate realistic looking images. Instead, styles are limited to those that look animated or sketched. ChatGPT will generate lifelike images, though. Apple Intelligence can be used to summarize documents, but only when you select text and select the Summarize option from Writing Tools. Apple Intelligence can't answer more specific questions about PDFs and documents, so ChatGPT does have an edge for that kind of query. ChatGPT Limitations When you ask ChatGPT a question through Siri, you need to make sure to read the answer right away because it doesn't stay on the screen long. Apple does not keep a record of it, either. If you're logged into ChatGPT, there is a history in your OpenAI account, but if you're not logged in, there's no way to save information that you've received from ChatGPT, and there's no log. Other Chatbots Apple has only added ChatGPT integration right now, but support for Google Gemini is planned in the future. Siri Apple Intelligence Features Coming Next Year There are several Siri features that are still in development, with Apple planning to add these capabilities to Siri next year. Timing isn't concrete yet, but rumors suggest we'll see them in iOS 18.4 in the spring. Personal Context Siri will be able to keep track of your emails, messages, files, photos, and more, learning more about you to help you complete tasks and keep track of what you've been sent. Onscreen Awareness Siri will be able to tell what's on your screen and complete actions involving whatever you're looking at. If someone texts you an address, for example, you can tell Siri to add it to their contact card. Or if you're looking at a photo and want to send it to someone, you can ask Siri to do it for you. Deeper App Integration Siri will be able to do more in and across apps, performing actions and completing tasks that are just not possible with the personal assistant right now. We don't have a full picture of what Siri will be capable of, but Apple has provided a few examples of what to expect. The Next Siri Phase After all of the Siri Apple Intelligence features have been implemented in iOS 18 , Apple plans to unveil the next-generation Siri, which will rely on large language models. An LLM version of Siri is already in development , and it will be able to better compete with chatbots like ChatGPT. LLM Siri will be able to hold ongoing conversations, and it will be more like speaking with a human. Large language model integration will let Siri perform more complex tasks, and in the future, Siri likely won't need to rely on ChatGPT. The updated version of Siri will replace the current version of Siri in the future. Apple is expected to announce LLM Siri in 2025 alongside the introduction of iOS 19 , but the update likely won't launch until spring 2026. Apple Intelligence Privacy Apple Intelligence was designed with privacy in mind, and many requests are handled on-device. All personal context learning, for example, is done with on-device intelligence and nothing leaves your iPhone or iPad. For requests that need the processing power of a cloud server, Apple is using Private Cloud Compute on Apple silicon machines to handle complex tasks while preserving user privacy. Apple promises that data is not stored and is used only for user requests. Apple Intelligence Compatible Devices Apple Intelligence is available on the iPhone 15 Pro, the iPhone 15 Pro Max, all iPhone 16 models, the iPad mini with A17 Pro chip, all iPads with an Apple silicon chip, and all Macs with an Apple silicon chip. Read More We've shared detailed guides on Genmoji and Image Playground already, plus we have an overall guide on the full set of Apple Intelligence features and a guide for the general features coming in iOS 18.2. Release Date iOS 18.2 and iPadOS 18.2 with Image Wand integration will be coming in December, with Apple likely planning for a December 9 software release.
PHOENIX — Two people are dead and three people are injured following a mobile home fire in north Phoenix, the city's fire department said. The fire was reported at a double mobile home fire near Cave Creek Road and Union Hills Drive. Three people were taken to the hospital in stable condition with burn injuries. Two people were pronounced dead at the scene. No other information was provided. You can now watch 12News content anytime, anywhere thanks to the 12News+ app! The free 12News+ app from 12News lets users stream live events — including daily newscasts like "Today in AZ" and "12 News" and our daily lifestyle program, "Arizona Midday"—on Roku and Amazon Fire TV . 12News+ showcases live video throughout the day for breaking news, local news, weather and even an occasional moment of Zen showcasing breathtaking sights from across Arizona. Users can also watch on-demand videos of top stories, local politics, I-Team investigations, Arizona-specific features and vintage videos from the 12News archives. Roku: Add the channel from the Roku store or by searching for "12 News KPNX." Amazon Fire TV: Search for "12 News KPNX" to find the free 12News+ app to add to your account , or have the 12News+ app delivered directly to your Amazon Fire TV through Amazon.com or the Amazon app. On your phone: Download the 12News app for the latest local breaking news straight to your phone. iTunes Google Play On your streaming device: Download 12News+ to your streaming device The free 12News+ app from 12News lets users stream live events — including daily newscasts like "Today in AZ" and "12 News" and our daily lifestyle program, "Arizona Midday"—on Roku and Amazon Fire TV. 12News+ showcases live video throughout the day for breaking news, local news, weather and even an occasional moment of Zen showcasing breathtaking sights from across Arizona. On social media: Find us on Facebook , Twitter , Instagram and YouTube .Latest on Philippe Clement’s future at Rangers amid swirling sack rumoursOKLAHOMA CITY (AP) — Alabama faces a tougher roadblock than it might appear in its quest to maintain positioning for the College Football Playoff. Sure, Oklahoma has struggled in its first Southeastern Conference season. The Sooners (5-5, 1-5 SEC) have lost four straight conference games. The Sooners have fired their offensive coordinator and they have the worst offense in the league. But they have a tough defense, too. Linebacker Danny Stutsman, a midseason AP All-American, anchors a nasty unit that has kept the Sooners competitive in losses at Ole Miss and Missouri. He ranks second in the SEC with 96 tackles. Defensive back Billy Bowman Jr. has scored four defensive touchdowns since the start of the 2023 season, tied for the most nationally. Defensive end R Mason Thomas has seven sacks, with six coming in the fourth quarter of close games. Alabama coach Kalen DeBoer is paying attention. “It’s going to take a great week of preparation,” DeBoer said. “A physical football team all around. Their defense is, I think, an extremely tough defense in all ways — just what they do with their scheme and then with their personnel, the way they fly around.” Plus, Oklahoma is motivated. It’s Senior Day for a program that would become bowl eligible with a win. Beating the seventh-ranked Crimson Tide could cure a lot of ills for the Sooners. “I think they know they could be a great example for what fight and what belief and what finishing and what improving and what proving people wrong looks like,” Oklahoma coach Brent Venables said. “And I think this is a group of guys that are committed to doing that.” Alabama (8-2, 4-2) has more answers than most. Jalen Milroe has passed for 15 touchdowns and rushed for 17. Freshman receiver Ryan Williams has 40 catches for 767 yards and eight touchdowns. “Yeah, incredibly explosive, and they have great playmakers everywhere," Venables said. “Certainly, it starts — everything goes through the quarterback.” There has been much talk about what a third loss would do to Alabama's playoff hopes. DeBoer said his team isn't focused on that. “I think we're really honed in and the guys really believe on and have understood the significance of really focusing on where we’re at right now,” he said. “We talk about the next play is the most important play, the next game is the most important game. We haven’t thought about anything beyond Oklahoma.” Milroe is only the fourth SEC quarterback since 2007 to have at least 15 passing touchdowns and 17 rushing touchdowns in a single season. The others won the Heisman Trophy during their seasons — Florida's Tim Tebow in 2007, Auburn's Cam Newton in 2010 and Texas A&M's Johnny Manziel in 2012. “I think it just starts with doing what’s best for the team, and that’s what Jalen is all about," DeBoer said. Since returning to the lineup early against South Carolina four games ago, Oklahoma quarterback Jackson Arnold has completed 70 of 112 passes for 705 yards with five touchdowns with no interceptions. Still, his fumble that was returned for a touchdown in the final minute against Missouri was the difference in a 30-23 loss. Arnold has dealt with significant criticism all season. “That goes along with that position at a place like the University of Oklahoma,” Venables said. “That’s a position that’s a little bit ... it’s a bit like the head coach position. There’s a different type of microscope and there’s a different type of focus and that’s okay he’s got broad shoulders to handle that.” Oklahoma running back Jovantae Barnes ran for career highs of 203 yards and three touchdowns against Maine two weeks ago, then he sat out last week's loss to Missouri. He's listed as questionable on this week's injury report. He leads the Sooners with 577 yards rushing this season. Venables is impressed with what DeBoer has done in his first year at Alabama since taking over for Nick Saban. “One of Kalen’s strengths as a football coach — a very successful coach — is he takes a group of players that he has, and their staff figures out what they can do,” Venables said. “They major in that, put them in position to be successful based on the players’ strengths. They’ve done a nice job of doing that throughout the course of the season.” Oklahoma beat heavily favored Alabama 45-31 in the Sugar Bowl to cap the 2013 season, a game that helped pump energy into the Sooner program under Bob Stoops. Alabama got revenge in 2018, beating the Sooners 45-34 in the College Football Playoff. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballPrayers Are Pouring In After 20-Year-Old College Football Player Dies
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